বুধবার, ২৪ এপ্রিল, ২০১৩

Senator Comes Out as State OKs Gay Marriage (ABC News)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/301091129?client_source=feed&format=rss

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Netflix $11.99 plan will allow simultaneous streaming on 4 devices

Netflix app

Company is 'shortly adding' new plans for US customers

Netflix subscribers who are liberal about sharing their login information with family and friends may have run into the 2-stream cap before. As of now, Netflix accounts can stream content on 2 devices at the same time; any more, and you'll get denied until someone else stops their online viewing.

Netflix has recognized that some customers need more than the current 2-stream maximum, and are planning to roll out $11.99 plans that will allow for 4 streams at once. Although Netflix thinks the need is there, they expect less than 1% of members to take them up on this new offer. While the numbers don't quite speak to the current need of the new plan, continuation of the company's recent growth could make this a more widely used option in the future.

There is no official date just yet, but if your family falls in the 1% that wants the ability to watch Netflix shows on your Google TV, computer, tablet, and phone all at the same time, these plans should be available very soon.

Source: Netflix, via: The Verge

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/Uezh8zkLw8g/story01.htm

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মঙ্গলবার, ২৩ এপ্রিল, ২০১৩

Boston Suspect's Legal Status A Test Case

Since 9/11, a debate has raged over whether the conflict with al Qaida and other jihadists should be treated more as a war or a crime. Now the same dispute is roiling over the fate of Dzhokar Tsarnaev, the 19-year-old ethnic Chechen and naturalized American who was captured by authorities in Boston Friday night after a dramatic day-long pursuit. Sen. Lindsey Graham, R-S.C., in a series of tweets, argued that Tsarnaev, one of two suspects in the fatal Boston Marathon bombings, should be treated as an enemy combatant and tried in a military tribunal.

In fact, that?s very unlikely to happen, not least because in the nearly 12 years since 9/11, U.S. authorities have failed to figure out precisely how to reconcile the suspension of legal rights for ?enemy combatants? with the Constitution. ?The military commissions are in a state of near-total collapse right now. The idea that you would take this kid from Boston and send him down there is laughable,? says Scott Horton, a human-rights lawyer based in New York.

By suspending Tsarnaev?s Miranda rights under the so-called ?public safety? exemption for more than a day or so, U.S. and Boston authorities are also taking a slight risk of tainting his prosecution?one that should be fairly open and shut -- in the same way other prosecutions under military tribunals have been damaged. ?Everything is being tainted by the intelligence community,? which has sought to gain evidence through extra-constitutional means that have sometimes included harsh interrogation, says Horton. ?It?s been given a free hand to do things.?

U.S. officials say they are concerned with other threats, perhaps including plots involving other bombs, that Tsarnaev might know about, but that is difficult to square with the declaration Friday night that the public was out of danger.

It is also not known what might have motivated Tsarnaev and his older brother, 26-year-old Tamarlan, to allegedly commit these acts. A series of postings on social media sites indicate that Tamarlan might have become somewhat radicalized by Islamist teachings, perhaps during a visit to Russia when he might have seen his father living in Makhachkala,?Dagestan, a city infused both with jihadist groups and counterterrorism apparatus set up by Russia?s FSB, or intelligence service. But Tamarlan was killed in a shootout with police, and authorities may well find that his seriously wounded younger brother was mainly following the elder Tsarnaev?s lead.

Graham, a former Air Force lawyer, posted a statement on his his Facebook page saying "it is absolutely vital the suspect be questioned for intelligence gathering purposes. We need to know about any possible future attacks which could take additional American lives," ? "The least of our worries is a criminal trial which will likely be held years from now."

Actually, with a huge array of detainees seemingly permanently under detention at Guantanamo, their fates undecided, and the rules for trying them still undetermined, the nature of Tsarnaev?s trial is a fairly significant issue.

Source: http://news.yahoo.com/boston-suspects-legal-status-test-case-100018669--politics.html

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Bugs produce diesel on demand

Bugs produce diesel on demand [ Back to EurekAlert! ] Public release date: 22-Apr-2013
[ | E-mail | Share Share ]

Contact: Jo Bowler
j.bowler@exeter.ac.uk
44-013-927-22062
University of Exeter

It sounds like science fiction but a team from the University of Exeter, with support from Shell, has developed a method to make bacteria produce diesel on demand. While the technology still faces many significant commercialisation challenges, the diesel, produced by special strains of E. coli bacteria, is almost identical to conventional diesel fuel and so does not need to be blended with petroleum products as is often required by biodiesels derived from plant oils. This also means that the diesel can be used with current supplies in existing infrastructure because engines, pipelines and tankers do not need to be modified. Biofuels with these characteristics are being termed 'drop-ins'.

Professor John Love from Biosciences at the University of Exeter said: "Producing a commercial biofuel that can be used without needing to modify vehicles has been the goal of this project from the outset. Replacing conventional diesel with a carbon neutral biofuel in commercial volumes would be a tremendous step towards meeting our target of an 80% reduction in greenhouse gas emissions by 2050. Global demand for energy is rising and a fuel that is independent of both global oil price fluctuations and political instability is an increasingly attractive prospect."

E. coli bacteria naturally turn sugars into fat to build their cell membranes. Synthetic fuel oil molecules can be created by harnessing this natural oil production process. Large scale manufacturing using E. coli as the catalyst is already commonplace in the pharmaceutical industry and, although the biodiesel is currently produced in tiny quantities in the laboratory, work will continue to see if this may be a viable commercial pathway to 'drop in' fuels.

Rob Lee from Shell Projects & Technology said: "We are proud of the work being done by Exeter in using advanced biotechnologies to create the specific hydrocarbon molecules that we know will continue to be in high demand in the future. While the technology still faces several hurdles to commercialisation, by exploring this new method of creating biofuel, along with other intelligent technologies, we hope they could help us to meet the challenges of limiting the rise in carbon dioxide emissions while responding to the growing global requirement for transport fuel."

###

This work was supported by a grant from Shell Research Ltd and a Biotechnology and Biological Sciences Research Council (BBSRC) Industry Interchange Partnership Grant.

About the University of Exeter

The Sunday Times University of the Year 2012-13, the University of Exeter is a Russell Group university and in the top one percent of institutions globally. It combines world-class research with very high levels of student satisfaction. Exeter has over 18,000 students and is ranked 7th in The Sunday Times University Guide, 10th in the UK in The Times Good University Guide 2012 and 10th in the Guardian University Guide. In the 2008 Research Assessment Exercise (RAE) 90% of the University's research was rated as being at internationally recognised levels and 16 of its 31 subjects are ranked in the top 10, with 27 subjects ranked in the top 20.

The University has invested strategically to deliver more than 350 million worth of new facilities across its campuses for 2012, including landmark new student services centres - the Forum in Exeter and The Exchange in Cornwall - and world-class new facilities for Biosciences, the Business School and the Environment and Sustainability Institute.

http://www.exeter.ac.uk

For further information:

Dr Jo Bowler
University of Exeter Press Office
Office: +44 (0)1392 722062
Mobile: +44(0)7827 309 332
j.bowler@exeter.ac.uk


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Bugs produce diesel on demand [ Back to EurekAlert! ] Public release date: 22-Apr-2013
[ | E-mail | Share Share ]

Contact: Jo Bowler
j.bowler@exeter.ac.uk
44-013-927-22062
University of Exeter

It sounds like science fiction but a team from the University of Exeter, with support from Shell, has developed a method to make bacteria produce diesel on demand. While the technology still faces many significant commercialisation challenges, the diesel, produced by special strains of E. coli bacteria, is almost identical to conventional diesel fuel and so does not need to be blended with petroleum products as is often required by biodiesels derived from plant oils. This also means that the diesel can be used with current supplies in existing infrastructure because engines, pipelines and tankers do not need to be modified. Biofuels with these characteristics are being termed 'drop-ins'.

Professor John Love from Biosciences at the University of Exeter said: "Producing a commercial biofuel that can be used without needing to modify vehicles has been the goal of this project from the outset. Replacing conventional diesel with a carbon neutral biofuel in commercial volumes would be a tremendous step towards meeting our target of an 80% reduction in greenhouse gas emissions by 2050. Global demand for energy is rising and a fuel that is independent of both global oil price fluctuations and political instability is an increasingly attractive prospect."

E. coli bacteria naturally turn sugars into fat to build their cell membranes. Synthetic fuel oil molecules can be created by harnessing this natural oil production process. Large scale manufacturing using E. coli as the catalyst is already commonplace in the pharmaceutical industry and, although the biodiesel is currently produced in tiny quantities in the laboratory, work will continue to see if this may be a viable commercial pathway to 'drop in' fuels.

Rob Lee from Shell Projects & Technology said: "We are proud of the work being done by Exeter in using advanced biotechnologies to create the specific hydrocarbon molecules that we know will continue to be in high demand in the future. While the technology still faces several hurdles to commercialisation, by exploring this new method of creating biofuel, along with other intelligent technologies, we hope they could help us to meet the challenges of limiting the rise in carbon dioxide emissions while responding to the growing global requirement for transport fuel."

###

This work was supported by a grant from Shell Research Ltd and a Biotechnology and Biological Sciences Research Council (BBSRC) Industry Interchange Partnership Grant.

About the University of Exeter

The Sunday Times University of the Year 2012-13, the University of Exeter is a Russell Group university and in the top one percent of institutions globally. It combines world-class research with very high levels of student satisfaction. Exeter has over 18,000 students and is ranked 7th in The Sunday Times University Guide, 10th in the UK in The Times Good University Guide 2012 and 10th in the Guardian University Guide. In the 2008 Research Assessment Exercise (RAE) 90% of the University's research was rated as being at internationally recognised levels and 16 of its 31 subjects are ranked in the top 10, with 27 subjects ranked in the top 20.

The University has invested strategically to deliver more than 350 million worth of new facilities across its campuses for 2012, including landmark new student services centres - the Forum in Exeter and The Exchange in Cornwall - and world-class new facilities for Biosciences, the Business School and the Environment and Sustainability Institute.

http://www.exeter.ac.uk

For further information:

Dr Jo Bowler
University of Exeter Press Office
Office: +44 (0)1392 722062
Mobile: +44(0)7827 309 332
j.bowler@exeter.ac.uk


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/uoe-bpd041713.php

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Genetic analysis tool opens new gene-regulation realms

Apr. 22, 2013 ? Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have developed a novel and powerful technique to identify the targets for a group of enzymes called RNA cytosine methyltransferases (RMTs) in human RNA. They applied their technique to a particular RMT, NSUN2, which has been implicated in mental retardation and cancers in humans, finding and validating many previously unknown RMT targets -- an indication of the technique's power. The research results were published online in the journal Nature Biotechnology on April 21.

"Although RMTs have been known for many years, virtually nothing is known about the majority of these enzymes in humans," said Bradley R. Cairns, co-author of the study and Senior Director of Basic Science at HCI. "This new technique will now allow the very rapid identification of the direct target RNAs for each human RMT, and we are excited about conducting that work."

Within all living cells, RNA acts as a critical intermediate in transmitting genetic information from DNA -- RNA is made from DNA and then used to encode proteins called enzymes that control cell functions. A process called cytosine methylation attaches methyl molecules to cytosine bases in DNA and RNA molecules. RMTs act as catalysts to allow methylation at particular locations in RNA molecules. Methylation can regulate the flow of genetic information (from RNA to protein production) in cells, and it can change the way RNA interacts with proteins.

RNA methylation is currently poorly understood, partly because of limitations in the technique currently used to identify which RNA molecules and cytosine bases are RMT targets. As each cell contains thousands of different types of RNA molecules, often with only a small percentage being targets for a specific RMT, the first step in a study of RNA methylation is to sort out and concentrate the precise target RNA molecules for a particular RMT, in a process called enrichment.

The work involved a novel enrichment method, which applied a special "chemical cross-linker" to physically join the RMT to an RNA that it is trying to methylate, said Vahid Khoddami, the study's co-author and a member of the Cairns Lab. "Our new technique takes advantage of the mechanism of the enzyme. The drug/crosslinker we used looks like cytosine, so it is incorporated in place of the cytosine in the RNA. The RMT tries to methylate this drug -- thinking it is a normal target cytosine -- but instead becomes crosslinked to the RNA, defining the precise location of the intended methylation. As our reaction-based method requires that the enzyme both bind the RNA and commit to the act of methylation, it greatly increases our identification of true positives," said Khoddami.

"This technique gives us 200-fold enrichment, when two-fold enrichment has been considered a great result in the past," said Khoddami. "In fact, for some RNA types, the enrichment is more than 700-fold."

After the enrichment process, high-throughput gene sequencing is used to analyze the RNA samples obtained.

"Our enrichment results were fantastic by themselves, but in the sequencing process we made another important discovery," Khoddami said. "We found that after sequencing, the target cytosine in the modified RNA instead appeared as an alternative molecule, guanosine, more than 50% of the time. After sequencing, you can look for these cytosine to guanosine transversions and know you have the precise target -- in a single experiment."

According to Khoddami, ten cytosine RMTs are known in humans, and only two of them have been partially characterized. "None of the other eight have been studied in the laboratory," he explained, "although some of them have been shown to have connections to cancer, infertility, and particular genetic disorders in humans.

"These diseases have been puzzling because previously we did not have the tools to analyze the RNA. Now we have beautiful tools," said Khoddami.

Cairns is a Howard Hughes Medical Institute investigator and a professor in the Department of Oncological Sciences at the University of Utah. He also holds a Jon and Karen Huntsman Presidential Professorship in Cancer Research. Khoddami is a doctoral candidate in the Cairns Lab at HCI.

This work was supported by the Howard Hughes Medical Institute, the Samuel Waxman Foundation, the Huntsman Cancer Foundation, and NCI CA24014.

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Story Source:

The above story is reprinted from materials provided by University of Utah Health Sciences, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Vahid Khoddami, Bradley R Cairns. Identification of direct targets and modified bases of RNA cytosine methyltransferases. Nature Biotechnology, 2013; DOI: 10.1038/nbt.2566

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/r-r12YwDFw0/130422132511.htm

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শুক্রবার, ১৯ এপ্রিল, ২০১৩

Breaking News : EFCC arrests Imo Finance Comm, AG over N1b ...

Soni Daniel, Regional Editor, North
Barely three weeks after the state House of Assembly removed the Imo Deputy Governor, Jude Agbaso, the Economic and Financial Crimes Commission, EFCC, has arrested the state Finance Commissioner, Okafor Chike John and the Accountant General, Eche Ezenna George, over the N1 billion road contract, for which Agbaso was impeached.

Comments are moderated. Please keep them clean and brief.

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Source: http://www.vanguardngr.com/2013/04/breaking-news-efcc-arrests-imo-finance-comm-ag-over-n1b-road-contract/

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